 | Anhydrous Methane Sulfonic Acid (AMSA) | Applications in the pharmaceutical industry Arkema AMSA enjoys wide use in the pharmaceutical industry due to its high acidity and high miscibility in aqueous and most organic media. Its uses include: - Formation of pharmacologically-acceptable API salts.
- Extraction, crystallization and purification of synthetic intermediates.
- Synthetic raw material.
- Acid catalyst, particularly for formation and removal of protecting groups.
- Dehydrating reaction solvent.
AMSA is a strong organic acid (pKa –1.92). As such, it is highly corrosive in its acid form. In contrast, methanesulfonate anion (MSA) has extremely low inherent toxicity. MSA is fully biodegradable and naturally-occurring, being a key species in the atmospheric sulfur cycle. |
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Please feel free to contact us to answer your questions about Arkema's AMSA. Send your e-mail requests to arkema.phil-oc-customer-service@arkemagroup.com and your request will be responded to immediately.
For pricing and availability questions please contact:
Thomas Lusch
Account Representative
(215) 419- 7041
Arkema Can Help You Resolve Genotoxic Issues
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